BLOCKADE OF THE ADAM8-FRA-1 COMPLEX ATTENUATES NEUROINFLAMMATION BY SUPPRESSING THE MAP3K4/MAPKS AXIS AFTER SPINAL CORD INJURY

Blockade of the ADAM8-Fra-1 complex attenuates neuroinflammation by suppressing the Map3k4/MAPKs axis after spinal cord injury

Abstract Background Mechanical spinal cord injury (SCI) is a deteriorative neurological disorder, causing secondary neuroinflammation and neuropathy.ADAM8 is thought to be an extracellular metalloproteinase, which regulates proteolysis and cell adherence, but whether its intracellular region is involved in regulating neuroinflammation in microglia

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An Effective Framework Using Spatial Correlation and Extreme Learning Machine for Moving Cast Shadow Detection

Moving cast shadows of moving objects significantly degrade the performance of many high-level computer vision applications such as object tracking, object classification, behavior recognition and scene interpretation.Because they possess similar motion characteristics with their objects, moving cast shadow detection is still challenging.In this pa

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Qualitative Chemical Characterization and Multidirectional Biological Investigation of Leaves and Bark Extracts of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae)

Anogeissus leiocarpus (DC.) Guill.& Perr.(Combretaceae) has a long history of use by folk populations for the management of multiple human ailments.Based on the published literature, there has been no attempt to conduct a comparative assessment of the biological activity and the phytochemical profiles of the leaves and stem bark of A.leiocarpus

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